姓名:蔡广研
导师类别:博士生导师
专业:内科学肾病
一、教育经历
1989~1996白求恩医科大学获硕士学位
1998~2001解放军总医院获博士学位
二、工作经历
1996~1998解放军总医院肾科住院医师
2001~2003解放军总医院肾科主治医师
2003~2008解放军总医院肾科副主任医师
2002~2013解放军总医院肾科副主任
2006~现在全军肾脏病研究所副所长
2008~2009解放军总医院肾脏病医院主任医师副教授
2009~现在解放军总医院肾脏病医院主任医师教授
2013~现在解放军总医院肾脏病科主任
三、研究方向(包括承担课题项目)
研究方向
1.老年肾损害的防治
2.IgA肾病的生物标志物及个体化诊疗研究
承担课题项目:
1.国家科技支撑计划课题任务书(2015BAI12B00)“重大疾病的防控策略、诊疗规范及效果评价研究”-“老年慢性肾脏病进展风险与防治的临床研究”(2015BAI12B06)2015.04.01-2017.12.31, 1595万元
2.国家973计划项目课题“器官和个体生物学衰老及老年疾病风险评价体系的研究 2013CB530805”起止时间2013.1-2017.8,123.6万
3.国家高技术研究发展计划(863计划)“IgA肾脏疾病分子分型和个体化诊疗技术” 435万元(编号2012AA02A512),起止时间2012.01-2015.12
四、学术兼职
1.中华肾脏病学会副主任委员
2.中国医师协会肾脏内科医师分会总干事长
3.全军肾脏病学专业委员会主任委员
4.北京肾脏病学会副主任委员
5.老年医学研究机构联盟常委
6.中国肾脏疾病防治联盟副主席
五、代表性论文著述(限10篇)
1.Wang WJ, Cai GY*, Chen XM. Cellular senescence, senescence-associated secretory phenotype, and chronic kidney disease. Oncotarget. 2017 Apr 21. doi: 10.18632/oncotarget.17327.
2.Liang S, Cai GY*, Duan ZY, Liu SW, Wu J, Lv Y, Hou K, Li ZX, Zhang XG, Chen XM. Urinary sediment miRNAs reflect tubulointerstitial damage and therapeutic response in IgA nephropathy. BMC Nephrol. 2017 Feb 15;18(1):63. doi: 10.1186/s12882-017-0482-0..
3.Song YH, Cai GY*, Xiao YF, Wang YP, Yuan BS, Xia YY, Wang SY, Chen P, Liu SW, Chen XM. Efficacy and safety of calcineurin inhibitor treatment for IgA nephropathy: a meta-analysis. BMC Nephrol. 2017 Feb 13;18(1):61.
4.Dong D, Cai GY*, Ning YC, Wang JC, Lv Y, Hong Q, Cui SY, Fu B, Guo YN, Chen XM. Alleviation of senescence and epithelial-mesenchymal transition in aging kidney by short-term caloric restriction and caloric restriction mimetics via modulation of AMPK/mTOR signaling. Oncotarget. 2016 Jan 28. doi: 10.18632/oncotarget.14884.
5.Wang WJ, Cai GY*, Ning YC, Cui J, Hong Q, Bai XY, Xu XM, Bu R, Sun XF, Chen XM. Hydrogen sulfide mediates the protection of dietary restriction against renal senescence in aged F344 rats. Sci Rep. 2016 Jul 26;6:30292. doi: 10.1038/srep30292.
6.Wang SY, Bu R, Zhang Q, Liang S, Wu J, Liu XZ, Cai GY*, Chen XM. Clinical, Pathological, and Prognostic Characteristics of Glomerulonephritis Related to Staphylococcal Infection. Medicine (Baltimore). 2016 Apr;95(15):e3386.
7.Duan ZY, Cai GY*, Bu R, Lu Y, Hou K, Chen XM. Selection of urinary sediment miRNAs as specific biomarkers of IgA nephropathy. Sci Rep. 2016 Mar 22;6:23498. doi: 10.1038/srep23498.
8.Xu XM, Cai GY*, Bu R, Wang WJ, Bai XY, Sun XF, Chen XM. Beneficial Effects of Caloric Restriction on Chronic Kidney Disease in Rodent Models: A Meta-Analysis and Systematic Review. PLoS One. 2015 Dec 22;10(12):e0144442. doi: 10.1371/journal.pone.0144442. eCollection 2015.
9.Li Mx, Cai Gy*. Diagnosis and Treatment of Nephrotic Syndrome in the Elderly. J Integr Nephrol Androl 2015;2:123-7.
10.Xu XM, Ning YC, Wang WJ, Liu JQ, Bai XY, Sun XF, Cai GY*, Chen XM. Anti-Inflamm-Aging Effects of Long-Term Caloric Restriction via Overexpression of SIGIRR to Inhibit NF-κB Signaling Pathway. Cell Physiol Biochem. 2015 Oct 5;37(4):1257-1270.
六、联系方式
1.通讯地址:北京市复兴路28号,解放军总医院肾脏疾病国家重点实验室
2.电话:
3. E-mail:caiguangyan@sina.com