姓名：张熙

导师类别：博士生导师

专业：神经病学

一、教育经历

1979.09-1984.07：第四军医大学，军医系，学士

1987.09-1990.07：第四军医大学，神经药理，硕士

1999.09-2002.07：中国协和医科大学，神经病学，博士。

二、工作经历

1984.09-1987.07：第四军医大学助教

1990.09-1999.07：原北京军区总医院神经内科

2002.08-今：解放军总医院南楼神经内科

三、研究方向（包括承担课题项目）

（一）研究方向

1．老年痴呆早期多模态影像特征的研究

2．睡眠生物节律紊乱与认知行为能力关系的研究

（二）承担课题项目：

1．军队重大项目（密级）；

2．军事脑计划（密级）；

3.北京脑科学项目（特殊作业群体睡眠节律紊乱危害评估关键技术的研究）

4.国家自然科学基金面上项目（基于脑网络组的阿尔茨海默病早期脑功能代偿机制的研究）

四、学术兼职

1.中国睡眠研究会常务理事；

2.睡眠生物节律专业委员会主任委员；

3.时间生物医学专业委员会副主任委员；

4.中国医疗保健国际交流促进会认知障碍专业委员会，常务委员；

5.中国认知科学会工作委员会委员

五、代表性论文著述（限10篇）

1. Zhang XiCA , Ma Lin, et al., A functional MRI evaluation of frontal dysfunction in patients with severe obstructive sleep apnea. Sleep Medicine. 2011, 12:335–340.

2. Zengqiang Zhang,Yong Liu, Tianzi Jiang, Bo Zhou, Ningyu An, Haitao Dai, Pan Wang, Yixuan Niu, Luning Wang, Xi ZhangCA. Altered Spontaneous Activity in Alzheimer’s Disease and Mild Cognitive Impairment Revealed by Regional Homogeneity NeurImage, 2012, 59, 1429-1440.

3.Hongxiang Yao, Yong Liu,∗, Bo Zhou, Zengqiang Zhang, Ningyu An, Pan Wang, Luning Wang, Xi ZhangCA, Tianzi Jiang，Decreased functional connectivity of the amygdala in Alzheimer’s disease revealed by resting-state fMRI. European Journal of Radiology, 82 (2013) 1531– 1538

4. Pan Wang, Xin Zhang, Yong Liu, Sainan Liu, Bo Zhou, Zengqiang Zhang, Hongxiang Yao, Xi ZhangCA, Tianzi Jiang. Perceptual and response interference in Alzheimer’s disease and mild cognitive impairment. Clinical Neurophysiology, 124,2013; 2389–2396

5. Bo Zhou, Yong Liu,* Zengqiang Zhang, Ningyu An, HongxiangYao, Pan Wang,

Luning Wang, Xi Zhang CA, and Tianzi Jiang, “Impaired functional connectivity of the thalamus in Alzheimer’s disease and mild cognitive impairment: a resting-state fMRI study,”Current Alzheimer Research, 2013,10(7); 754–766

6. Hongxiang Yao, Bo Zhou, Zengqiang Zhang, Pan Wang, Yan’e Guo, Yanchang Shang, Luning Wang, Xi Zhang CA , Ningyu An, and Yong Liu; Longitudinal Alteration of Amygdalar Functional Connectivity in Mild Cognitive Impairment Subjects Revealed by Resting-State fMRI. BRAIN CONNECTIVITY，Volume 4, Number 5, 2014.

7. Yane Guo, Zengqiang Zhang, Bo Zhou, Pan Wang, Hongxiang Yao, Minshao Yuan, Ningyu An, Haitao Dai, Luning Wang, Xi ZhangCA, Yong Liu, Grey-matter volume as a potential feature for the classification of Alzheimer’s disease and mild cognitive impairment: an exploratory study，Neuroscience Bulletin，June 1, 2014, 30(3): 477–489(IF=2.51).

8. Zengqiang Zhang, Yong Liu,* Bo Zhou, Jinlong Zheng, Hongxiang Yao, Ningyu An, Pan Wang, Yan’e Guo, Haitao Dai, Luning Wang, Siyun Shu, Xi ZhangCA, and Tianzi Jiang,* Altered Functional Connectivity of the Marginal Division in Alzheimer’s Disease. Current Alzheimer Research, 2014,11(2), 145-155.(IF=3.89)

9. Pan Wang,Yun Kwok Wing, Jianli Xing,Yong Liu, Bo Zhou. Zengqiang Zhang, Hongxiang Yao, Yan’e Guo, Yanchang Shang, Xi ZhangCA, Rapid eye movement sleep behavior disorder in patients with probable Alzheimer’s disease. Aging Clin Exp Res, DOI 10.1007/s40520-015-0382-8. (IF=1.22)

10.Pan Wang, Bo Zhou, Hongxiang Yao, Yafeng Zhan, Zengqiang Zhang, Yue Cui, Kaibin Xu, Jianhua Ma, Luning Wang, Ningyu An, Xi ZhangCA, Yong Liu, and Tianzi Jiang, Aberrant intra- and inter-network connectivity architectures in Alzheimer's disease and mild cognitive impairment, Scientific Reports, 10/2015; 5:14824.

六、联系方式

1．通讯地址：北京海淀区复兴路28号

2．电话：

3． E-mail：zhangxi@301hospital.com.cn